Non-toxic reactions to food can be immune mediated (food allergy) or non-immune mediated (food intolerance). Intolerance to food may be enzymatic or pharmacological but in certain instances, it is undefined. Such reactions are independent of IgE mediation. Adverse reactions affect gastrointestinal, skin & pulmonary systems.
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Circulating Testosterone consists of testosterone bound to SHBG and the bioavailable (Free & Bound to Albumin). The latter is biologically active. In men approximately 40% of Total testosterone is albumin bound while in women approximately 20% is albumin bound. Free testosterone can be used as second-level test for suspected increases or decreases in physiologically active testosterone. This test helps to assess androgen status in cases with suspected or known Sex hormone-binding globulin-binding abnormalities; assesses functional circulating testosterone in early pubertal boys and older men; assesses functional circulating testosterone in women with symptoms or signs of hyperandrogenism but normal total testosterone levels.
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