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ANA is useful in the diagnosis of patients with autoimmune diseases such as SLE, Mixed connective tissue disease, Rheumatoid arthritis, Sjogren’s syndrome, Progressive systemic sclerosis and CREST syndrome. The incidence of low titre ANA positivity increases with age in normal individuals. many drugs like Hydralazine and Procainamide may induce ANA production.
Arthritic disorders affect majority of the population, varying in severity. Many of these disorders are self limiting conditions requiring minimal evaluation and symptomatic therapy. However several patients show persistent musculo-skeletal symptoms that requires laboratory testing to establish diagnosis and document the pathological process. Complement mediated immune complex deposition may also result in arthritic changes.
Arthritic disorders affect majority of the population, varying in severity. Many of these disorders are self limiting conditions requiring minimal evaluation and symptomatic therapy. However several patients show persistent musculo-skeletal symptoms that requires laboratory testing to establish diagnosis and document the pathological process. Complement mediated immune complex deposition may also result in arthritic changes.
Arthritic disorders affect majority of the population, varying in severity. Many of these disorders are self limiting conditions requiring minimal evaluation and symptomatic therapy. However several patients show persistent musculo-skeletal symptoms that requires laboratory testing to establish diagnosis and document the pathological process. Complement mediated immune complex deposition may also result in arthritic changes.