An arthritis profile is a series of blood tests used to help diagnose and assess arthritis, focusing on inflammatory markers and autoimmune activity. It can help determine the type and severity of arthritis and guide treatment plans.
Here’s a more detailed explanation:
Purpose:
The arthritis profile helps doctors understand the underlying causes of arthritis, differentiate between different types (like rheumatoid arthritis and osteoarthritis), and monitor the effectiveness of treatment.
Tests Included:
Common tests in an arthritis profile include:
C-reactive protein (CRP):A marker of inflammation in the body.
Erythrocyte sedimentation rate (ESR):Another marker of inflammation.
Rheumatoid factor (RF):A protein found in the blood of people with rheumatoid arthritis.
Anti-CCP antibodies:A type of autoantibody found in people with rheumatoid arthritis.
Antinuclear antibodies (ANA):Autoantibodies that can be elevated in various autoimmune conditions.
Complete blood count (CBC):A general blood test that can reveal signs of inflammation or infection.
Uric acid:Elevated levels can indicate gout, a type of arthritis.
Antistreptolysin O (ASO):An antibody that can be elevated after a streptococcal infection, which can sometimes trigger arthritis.
How it’s done:
The arthritis profile is typically a blood test, but may also include a urine sample.
Interpreting Results:
Elevated levels of inflammatory markers (CRP, ESR) or the presence of certain autoantibodies (RF, anti-CCP) can suggest arthritis or other autoimmune conditions.
Types of Arthritis:
The tests can help differentiate between different types of arthritis, such as rheumatoid arthritis, osteoarthritis, psoriatic arthritis, and other inflammatory conditions.
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The BioFire-Respiratory Panel 2.1 is a comprehensive, multiplex PCR-based diagnostic test that simultaneously detects and identifies 22 common respiratory pathogens—including SARS-CoV-2, influenza A/B, RSV, rhinovirus/enterovirus, adenovirus and several bacteria—from a single nasopharyngeal swab sample. The panel offers rapid, accurate and actionable insights for clinicians to differentiate between viral and bacterial infections.
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The BioFire Blood Culture Identification (BCID) panel is a rapid molecular test used to identify the causative agent of bloodstream infections (BSIs) in patients with positive blood cultures. It detects multiple pathogens and antimicrobial resistance genes in a single test, aiding in the timely management of sepsis and other BSI-related conditions. The panel is typically used on the BioFire FilmArray system.
Here’s a more detailed breakdown:
Purpose:
Rapid Identification:
The BCID panel helps quickly identify the specific bacteria, fungi, or other microorganisms responsible for a bloodstream infection.
Antimicrobial Resistance Detection:
It also detects genetic markers associated with antimicrobial resistance, allowing for better-targeted antibiotic therapy.
Improved Sepsis Management:
Rapid identification and resistance detection can lead to quicker adjustment of broad-spectrum antibiotics to more specific regimens, potentially reducing antibiotic use and hospital stay.
How it Works:
Multiplex PCR: The panel uses a multiplex PCR (polymerase chain reaction) technology to detect multiple targets simultaneously.
FilmArray System: It is designed for use with the BioFire FilmArray system.
Sample Preparation: A positive blood culture sample is processed, and the DNA is amplified and analyzed within the FilmArray system.
Benefits:
Faster Results:
The test provides results in about an hour from a positive blood culture, compared to days for traditional culture-based methods.
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The BioFire Pneumonia Plus Panel is a rapid, multiplex PCR-based diagnostic test that detects over 34 bacterial, viral and antimicrobial resistance targets directly from lower respiratory tract specimens such as sputum or bronchoalveolar lavage (BAL). It identifies community- and hospital-acquired pneumonia and several key resistance genes (including mecA/C, CTX-M and carbapenemases). The test enables clinicians to make faster and informed decisions for improving patient outcomes.
The BioFire Pneumonia Panel (PN panel) is a rapid PCR test that identifies bacterial and viral pathogens in lower respiratory tract samples like sputum, bronchoalveolar lavage, and endotracheal aspirates. It’s used to diagnose pneumonia and other respiratory infections. The panel can detect a wide range of pathogens, including common bacteria and viruses, as well as genetic markers of antimicrobial resistance.
Key features of the BioFire Pneumonia Panel:
Rapid Results:
The panel provides results within about an hour, significantly faster than traditional culture-based methods.
Comprehensive Detection:
The panel identifies a wide range of pathogens, including 18 bacteria, 8 viruses, and 7 antimicrobial resistance genes.
Semi-quantitative Results:
For 15 common bacteria, the panel provides semiquantitative results, which can help determine whether an organism is a colonizer or a pathogen.
Enhanced Diagnostic Accuracy:
The panel can detect pathogens that might be missed by standard culture, potentially improving diagnostic accuracy and guiding antimicrobial prescribing.
Improved Clinical Decision-Making:
The rapid results and comprehensive pathogen detection can help clinicians make more informed decisions about treatment, potentially leading to faster and more targeted antimicrobial therapy.
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