Neisseria gonorrhoeae PCR, also known as Gonorrhoea PCR, is a test that uses a sample (like a urine or swab) to detect the presence of the bacteria Neisseria gonorrhoeae using a PCR (Polymerase Chain Reaction) method. This test is highly sensitive and specific, meaning it can accurately identify the bacteria and distinguish it from other microorganisms, according to Phadke Labs.
Here’s a more detailed breakdown:
What it is:
PCR is a molecular testing technique that amplifies specific DNA sequences, making them detectable and allowing for identification of the bacteria.
Why it’s used:
PCR is considered a highly sensitive and accurate test for diagnosing gonorrhoea, which is a sexually transmitted infection (STI) caused by Neisseria gonorrhoeae.
How it works:
A sample is taken from the affected area (e.g., urethra, cervix, rectum) and the DNA is extracted. Then, PCR is used to amplify a specific gene sequence from the Neisseria gonorrhoeae bacteria.
What it detects:
A positive result indicates the presence of the Neisseria gonorrhoeae DNA, suggesting a current infection.
When it’s recommended:
PCR testing is often recommended for individuals who may be at risk for gonorrhea, including those with symptoms, those who have multiple partners, and those in certain high-risk groups.
Important Considerations:
False-negative results:Can occur due to improper specimen collection, technical errors, or concurrent antibiotic therapy.
Co-infection:PCR can often be paired with a Chlamydia test as both STIs are commonly found together.
Confirmation:Positive results may be confirmed by repeat testing or culture in some cases,
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Neurotropic B group vitamins play crucial roles as coenzymes in the nervous system. Particularly Vitamin B1 (Thiamine), Vitamin B6 (Pyridoxine) & Vitamin B12 (Cobalamin) contribute essentially to the maintenance of a healthy nervous system. Vitamin B1 acts as a site-directed antioxidant; Vitamin B6 balances nerve metabolism; Vitamin B12 maintains myelin sheaths.Their importance is highlighted by many neurological diseases related to deficiencies in one or more of these vitamins. Deficiencies of these vitamins can occur mainly in elderly individuals, diabetics, alcoholics, dialysis patients, patients with gastrointestinal diseases etc. and may lead to neurological disturbances e.g. Peripheral neuropathy. On the other hand neurological adverse effects like ataxia, sensory neuropathy etc. have been demonstrated with long-term or high dose use of these vitamins specially Vitamin B6
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This is a general health check package, suitable for all and it covers all essential parameters. It is ideal for someone who wishes to get routine health check-up done. Parameters pertaining to all the major organs are covered. Package includes Thyroid Profile
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What is NIPT Test?
NIPT is a simple, safe, and non invasive prenatal screening test that provides assurance to expectant parents with accurate genetic information about their babyNIPT Test uses advanced bioinformatics technology to evaluate fetal DNA (of placental origin) in maternal blood to identify genetic variations leading to disorders.
What are the conditions that NIPT, NIPT Twins, and NIPT Advanced can detect?
NIPT can detect common Aneuploidies and Sex Chromosome Abnormalities.
NIPT
Trisomy 21 (Down Syndrome)
Trisomy 18 (Edwards’ Syndrome)
Trisomy 13 (Patau syndrome)
Turner Syndrome (Monosomy X/XO)
Klinefelter Syndrome (XXY)
Triple X (XXX)
Jacob’s Syndrome (XYY)
NIPT Advanced
Rare Autosomal Aneuploidies (RAA) include trisomies in chromosomes other than 21, 18 and 13 and monosomies in all 22 chromosomes.
NIPT Advanced screens for RAAs in addition to Trisomy 13, 18, 21 and sex chromosomes.
NIPT Twins
Trisomy 21
Trisomy 18
Trisomy 13
Here’s a more detailed explanation:
NIPT (Non-Invasive Prenatal Testing):This is the most common and widely used term for the test.
NIPS (Non-Invasive Prenatal Screening):Some healthcare professionals and organizations prefer this term, as NIPT is a screening test, not a diagnostic test.
cfDNA (cell-free DNA) screening:This term refers to the type of DNA analyzed in the test, which is the DNA fragments circulating in the pregnant woman’s blood.
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N-terminal precursor of brain natriuretic peptide (NT-proBNP) are released from myocardial cells in response to volume expansion and increased wall tension. They are well established rule-out tools for cardiac disease in unselected communities. NT-proBNP value <125 pg/mL excludes cardiac dysfunction with a high level of certainty in patients presenting with dyspnea. As the value increases heart failure becomes more likely. NT-proBNP levels are correlated with New York Heart Association (NYHA) functional classes for CHF. However, the role of natriuretic peptides extends beyond heart failure diagnosis; it is a clinical support tool in risk stratification & management in both inpatient and outpatient settings. Recent studies have shown that it can also be used for Cardiovascular risk assessment in asymptomatic patients with Type 2 Diabetes Mellitus.
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